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. 2021 Jul 15;117(1):181–264. [Article in Portuguese] doi: 10.36660/abc.20210180
Anticoagulants
Fondaparinux 2.5 mg subcutaneously once a day can be used for 8 days or until hospital discharge as an alternative to enoxaparin, especially in patients with a high risk of bleeding. I B
Monitor anti-factor Xa in patients with creatinine clearance between 15 and 30 mL/min and in obese patients (100 to 150 kg) who are using enoxaparin. IIa B
Enoxaparin is preferential to UFH in patients with creatinine clearance ≥15 mL/min/1.73 m²), unless myocardial revascularization surgery is scheduled in the next 24 h. IIa B
UFH is preferential in the emergency department or hemodynamics unit in very high-risk patients with immediate catheterization scheduled (< 2 h). IIa C
Enoxaparin can be used in patients with creatinine clearance < 15 mL/min and weight > 150 kg. III
Fondaparinux can be used in patients with creatinine clearance < 20 mL/min. III