Table 1.
Patient | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 |
---|---|---|---|---|---|---|---|---|---|
Description | Index case | Cleaner | Nurse | Nurse | Nurse practitioner | The index patient's family | An un-infected in-patient's family who stayed in the ward 5C | An in-patient admitted to 5C before the cluster was identified | The index patient's family |
Age (year) | 57 | 56 | 29 | 27 | 42 | 26 | 58 | 56 | 24 |
Sex | Female | Female | Female | Female | Female | Female | Female | Female | Male |
Underlying conditions | Heart failure, coronary artery disease | Hypertension | Pregnancy | No | No | No | Hypertension | Liver cirrhosis, hepatocellular carcinoma | No |
Presenting symptoms | Fever and cough | Cough | Cough and rhinorrhea | Cough and rhinorrhea | Muscle ache and mild fever (37.5 °C) | No symptoms | Fever, cough, and muscle ache | Cough | Cough |
Chest radiograph | Pneumonia | Normal | NA | Normal | Normal | Normal | Pneumonia | Pneumonia | NA |
HRCT | GGO | GGO | NA | Normal | GGO | NA | GGO | GGO | NA |
LOS | 43 | 14 | 23 | 21 | 31 | NA | 39 | 28 | NA |
Outcome | Mortality | Survival | Survival | Survival | Survival | Survival | Survival | Survival | Survival |
White blood cell count (109/L) | 2.1 | 9.1 | 5.3 | 6.4 | 3.6 | NA | 7.1 | 3.4 | NA |
Lymphocyte (109/L) | 0.2 | 2.4 | 1.3 | 2.0 | 1.2 | NA | 1.2 | 0.7 | NA |
Platelet count (109/L) | 158 | 325 | 249 | 273 | 174 | NA | 198 | 186 | NA |
D-dimer (ng/mL) | 1902 | 191 | 574 | <170 | <170 | NA | 429 | 1539 | NA |
C-reactive protein (mg/L) | 73.6 | 2.5 | 2.6 | 1.5 | 3.4 | NA | 66 | 10.4 | NA |
Lactate dehydrogenase (U/L) | 690 | 177 | 189 | 212 | 227 | NA | 327 | 265 | NA |
Creatine (mg/dL) | 1.4 | 0.6 | 0.4 | 0.7 | 0.6 | NA | 0.6 | 0.6 | NA |
AST (U/L) | 45 | 27 | 21 | 21 | 38 | NA | 32 | 41 | NA |
ALT (U/L) | 16 | 25 | 18 | 13 | 23 | NA | 29 | 31 | NA |
Bilirubin (mg/dL) | 1.3 | 1.2 | 0.2 | 0.3 | 0.7 | NA | 0.5 | 0.3 | NA |
Ct valuea | |||||||||
E gene | 23.9 | 26.6 | 28.8 | 26.4 | 29.9 | 24.1 | 27.5 | 26.6 | 24.95 |
RdRp-1 | 29.8 | 26.9 | 25.6 | 24.0 | 37.6 | 25.2 | 29.8 | 28.1 | 27.03 |
RdRp-2 | 24.2 | 28.0 | 25.6 | 23.9 | 30.8 | 25.4 | 26.7 | 27.3 | 26.02 |
N gene | 28.5 | 26.6 | 28.8 | 26.4 | 32.3 | 28.1 | 31.7 | 32.0 | 29.73 |
Ct = cycles of thresholds; GGO = ground-glass opacities; HRCT = High-resolution computed tomography; LOS = length of stay; NA = not available.
RT-PCR of the respiratory specimens collected at the time of diagnosis.