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. 2021 Jul 21;7(30):eabg3147. doi: 10.1126/sciadv.abg3147

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Copyright © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).

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Fig. 6 — (A) Ternary complex formation between the DOCK5 DHR-2 domain, Rac1, and the ELMO1 PH domain according to the cryo-EM structure. The color codes are as follows: orange, ELMO1; green, DOCK5; yellow, Rac1. (B) The crystal structure of the DOCK9 (DHR-2)–Cdc42 complex (PDB code 2WM9) is docked to ELMO1 by replacing DOCK5 (DHR-2)–Rac1 in (A). Blue, DOCK9; purple, Cdc42.