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. 2021 Jul 23;100(29):e26667. doi: 10.1097/MD.0000000000026667

Table 2.

Disease phases classification criteria2.

Disease phases classification ALT HBV DNA HBeAg
Immune active (IA) Elevated >20,000 IU/mL Positive
>2000 IU/mL Negative
Inactive CHB (IC) Normal Low HBV DNA level Negative
Immune tolerance (IT) Normal >1 million IU/mL Positive
Gray zone (GZ) Not classified as IC, IT, or IA

Upper limit of normal (ULN) of ALT: 30 U/L for males and 19 U/L for females. ALT = alanine aminotransferase, HBV = hepatitis B virus.