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. 2021 Jul;108:137–144. doi: 10.1016/j.ijid.2021.05.008

Table 1.

Summary of investigations for blood samples from five malaria patients referred to the MRL following inconsistent RDT results.

Sample reference Travel history Carestart
Pf HRP
Binax
Pf HRP
Optimal
Pf LDH
Carestart
Pan-genus LDH
Binax
Pan-genus aldolase
Optimal
Pan-genus LDH
S105 Sudan NEG NEG POS POS POS POS
S160 Uganda WEAK NEG/WEAK POS POS POS POS
S194 Ethiopia NEG NEG POS POS POS POS
S204 Sudan NEG NEG POS POS POS POS
S227 Zambia NEG NEG NEG NEG NEG NEG

Pf: P. falciparum-specific.

LDH: parasite lactate dehydrogenase detectable by specific monoclonal antibodies (MAb) in the RDT.

Pan-genus: where RDT deploys an MAb that detects antigens from all members of the genus Plasmodium.