Table 2.
Comparison of variables between negative and positive test result in patient collected samples separated by collection method
| Sample type | Variable | Negative | Positive | p-value |
|---|---|---|---|---|
| MS | N | 3 | 59 | |
| Ct value of professionally collected cOP/NP, median (IQR) | 27.2 (27.1, 30.4) | 20.4 (17.2, 22.9) | 0.008 | |
| Female | 1 (33.3%) | 30 (50.8%) | 1.000 | |
| Age in years, median (range) | 48.0 (35.0, 53.0) | 31.0 (17.0, 66.0) | 0.064 | |
| Number of symptoms, median (range) | 7.0 (7.0, 7.0) | 5.0 (2.0, 10.0) | 0.335 | |
| Symptom interval in days, median (range) | 11.0 (4.0, 15.0) | 4.0 (2.0, 12.0) | 0.083 | |
| German is not first language | 3 (100.0%) | 16 (27.1%) | 0.026 | |
| No. of mistakes during sampling procedure, median (range) | 2.0 (2.0, 3.0) | 0.0 (0.0, 3.0) | 0.005 | |
| SN | N | 3 | 59 | |
| Ct value of professionally collected cOP/NP, median (IQR) | 29.1 (28.1, 31.4) | 20.4 (17.2, 22.9) | 0.006 | |
| Female | 1 (33.3%) | 30 (50.8%) | 1.000 | |
| Age in years, median (range) | 35.0 (19.0, 48.0) | 31.0 (17.0, 66.0) | 0.948 | |
| Number of symptoms, median (range) | 3.0 (3.0, 3.0) | 5.0 (2.0, 10.0) | 0.127 | |
| Symptom interval in days, median (range) | 12.0 (4.0, 15.0) | 4.0 (2.0, 11.0) | 0.077 | |
| German is not first language | 3 (100.0%) | 16 (27.1%) | 0.026 | |
| No. of mistakes during sampling procedure, median (range) | 2.0 (1.0, 3.0) | 0.0 (0.0, 3.0) | 0.012 | |
| GW | N | 7 | 55 | |
| Ct value of professionally collected OP/NP, median (IQR) | 26.6 (23.4, 28.1) | 20.1(17.1, 22.3) | < 0.001 | |
| Female | 4 (57.1%) | 27 (49.1%) | 1.000 | |
| Age in years, median (range) | 34.0 (19.0, 48.0) | 31.0 (17.0, 66.0) | 0.798 | |
| Number of symptoms, median (range) | 6.0 (3.0, 9.0) | 5.0 (2.0, 10.0) | 0.794 | |
| Symptom interval in days, median (range) | 4.0 (3.0, 15.0) | 5.0 (2.0, 11.0) | 0.804 | |
| German is not first language | 4 (57.1%) | 15(27.3%) | 0.187 | |
| No. of mistakes during sampling procedure, median (range) | 0.0 (0.0, 2.0) | 0.0 (0.0, 2.0) | 0.426 |
MS – Multis-swab (cheek, tongue, nares), SN – Saliva-nasal (saliva, nasal vestibule), GW – gargle water. A patient sample was considered positive when either the e-gene or the ORF1ab-gene or both were detected.