Table 5.
Postsurgical data
| Control group | AP group | AC group | p value | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| (n = 270) | Interruption (n = 7) | Continuing (n = 39) | Total (n = 46) | Interruption (n = 7) | Heparinization (n = 10) | Total (n = 17) | |||||||||
| A | B1 | B2 | B | C1 | C2 | C | A vs. B1 | A vs. B2 | A vs. B | B1 vs. B2 | A vs. C1 | A vs. C2 | A vs. C | C1 vs. C2 | |
| Drain output on POD1 (ml) mean ± SD | 124.8 ± 100.3 | 114.7 ± 38.6 | 145.6 ± 95.5 | 140.6 ± 89.9 | 89.0 ± 39.3 | 127.3 ± 153.5 | 111.5 ± 121.9 | 0.79 | 0.23 | 0.31 | 0.41 | 0.35 | 0.94 | 0.6 | 0.55 |
| Catheter placement (days) | |||||||||||||||
| Mean ± SD | 9.0 ± 9.5 | 10.3 ± 11.3 | 9.3 ± 8.8 | 9.4 ± 9.2 | 11.7 ± 14.0 | 12.9 ± 9.1 | 12.4 ± 11.4 | 0.33 | 0.87 | 0.6 | 0.48 | 0.89 | 0.01 | 0.04 | 0.17 |
| Median (IQR) | 6 (6, 7) | 6 (5, 6) | 6 (6, 6) | 6 (6, 6) | 6 (6, 6) | 8 (6, 19) | 6 (6, 15) | ||||||||
| Hospitalization (days) | |||||||||||||||
| Mean ± SD | 7.5 ± 1.6 | 7.3 ± 1.2 | 7.6 ± 2.2 | 7.6 ± 2.1 | 6.9 ± 0.3 | 9.9 ± 2.7 | 8.6 ± 2.6 | 0.65 | 0.29 | 0.25 | 0.74 | 0.21 | < 0.01 | 0.049 | < 0.01 |
| Median (IQR) | 7 (7, 8) | 7 (6, 9) | 7 (7, 7) | 7 (7, 7) | 7 (7, 7) | 9 (8, 12) | 7 (7, 9) | ||||||||
| Blood transfusion after surgery, n (%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | NA | |||||||
| Bleeding complications*, n (%) | |||||||||||||||
| Gd0 | 260 (96.3%) | 7 (100%) | 37 (94.9%) | 44 (95.7%) | 5 (71.4%) | 8 (80.0%) | 13 (76.5%) | 0.87 | 0.55 | 0.63 | > 0.99 | < 0.01 | 0.02 | < 0.01 | 0.46 |
| Gd1 | 3 (1.1%) | 0 (0%) | 0 (0%) | 0 (0%) | 2 (28.6%) | 1 (10.0%) | 3 (17.6%) | ||||||||
| Gd2 | 7 (2.6%) | 0 (0%) | 2 (5.1%) | 2 (4.3%) | 0 (0%) | 1 (10.0%) | 1 (5.9%) | ||||||||
| Complications* during 90 days after surgery, n (%) | |||||||||||||||
| Gd0 | 191 (70.5%) | 4 (57.1%) | 28 (71.8%) | 32 (69.6%) | 4 (57.1%) | 5 (50.0%) | 9 (52.9%) | 0.74 | 0.86 | 0.78 | 0.67 | 0.12 | 0.39 | 0.08 | 0.44 |
| Gd1 | 35 (12.9%) | 1 (14.3%) | 5 (12.8%) | 6 (13.0%) | 3 (42.9%) | 3 (30.0%) | 6 (35.3%) | ||||||||
| Gd2 | 39 (14.8%) | 2 (28.6%) | 6 (15.4%) | 8 (17.4%) | 0 (0%) | 2 (20.0%) | 2 (11.8%) | ||||||||
| Gd3 | 5 (1.8%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | ||||||||
| Gd4. 5 | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | ||||||||
AP antiplatelet, AC anticoagulant, POD postoperative day, Gd grade, NA not assessed
*Complications according to Clavien–Dindo classification