TABLE 2.
Main and interaction effects of APOE e4 and CBF on pattern separation
| Variables | Coefficient (SE) | Standardized effects | p | LLCI | ULCI | |
|---|---|---|---|---|---|---|
| Right | Constant | 13.66 (8.05) | .092 | −2.27 | 29.59 | |
| Sex | 11.15 (3.97) | 0.25 | .006 | 3.28 | 19.01 | |
| Age | −0.82 (0.30) | −0.23 | .007 | −1.41 | −0.23 | |
| Education | 1.83 (0.89) | 0.18 | .043 | 0.06 | 3.59 | |
| Precentral CBF | −0.34 (0.34) | −0.10 | .329 | −1.02 | 0.34 | |
| Hippocampal CBF | 0.07 (0.28) | −0.28 | .808 | −0.49 | 0.63 | |
| APOE status (+ vs. −) | −6.38 (4.10) | −0.13 | .122 | −14.50 | 1.74 | |
| APOE × hippocampal CBF | 1.24 (0.58) | 0.36 | .035 | 0.09 | 2.38 | |
| Left | Constant | 12.25 (8.51) | .15 | −4.60 | 29.11 | |
| Sex | 9.50 (3.88) | 0.22 | .015 | 1.81 | 17.19 | |
| Age | −0.80 (0.30) | −0.23 | .009 | −1.40 | −0.20 | |
| Education | 1.65 (0.90) | 0.16 | .071 | −0.14 | 3.43 | |
| Precentral CBF | −0.14 (0.34) | −0.05 | .676 | −0.80 | 0.52 | |
| Hippocampal CBF | −0.10 (0.36) | −0.28 | .772 | −0.81 | 0.60 | |
| APOE status (+ vs. −) | −5.98 (4.10) | −0.12 | .148 | −14.10 | 2.15 | |
| APOE × hippocampal CBF | 1.17(0.61) | 0.28 | .058 | −0.04 | 2.39 | |
Note: Significant effects (p < .05) are shown in bold.
Abbreviation: CBF, cerebral blood flow.