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. 2021 Jul 21;7:63. doi: 10.1038/s41531-021-00202-w

Table 2.

Summary of matched case-control studies on the association of hypertension with risk of Parkinson’s disease.

Study Country Sample size Assessment of hypertension OR (95% CI) P value Matching criteria
Current study Singapore 671 PD, 671 controls Questionnaire and medical record 1.86 (1.46–2.38) <0.0001 Gender, age
Paganini-Hill17 USA 395 PD, 2320 controls Questionnaire 0.71 (0.56–0.89) None Gender, age, vital status
Powers et al.16 USA Males: 217 PD, 298 controls Questionnaire 0.80 (0.55–1.17) None Gender, age, area
Becker et al.15 UK 3637 PD, 3637 controls Medical record 0.83 (0.74–0.92) 0.001 Gender, age, general practice, index date, and duration of previous history