Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jul 21;11:14863. doi: 10.1038/s41598-021-94365-4

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

HBMSC-derived exosomes modulate gene expression of hTMCs exposed to H₂O₂. (a) Heat map of 23 DE miRNA between Exo group and control group. The horizontal axis is log2 (expression value + 1) and the vertical axis is a gene. Line indicates DE miRNA, red indicates high expression, and green indicates low expression. (a) was drawn using R 3.6.3 for Windows (URL: https://cran.r-project.org/bin/windows/base/old/3.6.3/R-3.6.3-win.exe). (b) DEmiRNA-DEmRNA regulation network. Circle indicates DE mRNA, inverted triangle indicates DE miRNA, green indicates down-regulation and red indicates up-regulation. 12 miRNA-mRNA targeting pairs were predicted in the network. (c) Delncrna-DEmRNA interactional subnet. Square indicates lncNRA, Circle indicates mRNA. The data of microRNA, LncRNA and mRNA were presented in Supplementary Tables S6 and S7. (b,c) were drawn using Cytoscape 3.7.2 (URL: https://github.com/cytoscape/cytoscape/releases/download/3.7.2/cytoscape-3.7.2.zip).