Table 4.

The characteristics of ARDS in children with hematologic neoplasms: agranulocytosis and non-agranulocytosis group.

	Agranulocytosis (n = 18)	Non-agranulocytosis (n = 27)	P-value
Clinical outcome [n (%)]			1.000
Survivor	8 (44.4%)	12 (44.4%)
Non-survivor	10 (55.6%)	15 (55.6%)
Sex (male/female)	11/7	15/12	0.712
Age (n %)			0.744
<6 months	1 (5.6%)	1 (3.7%)
<2 years	5 (27.8%)	4 (14.8%)
2–6 years	8 (44.4%)	15 (55.6%)
7–17 years	4 (22.2%)	7 (25.9%)
Total length of mechanical ventilation [($\overline{x}\pm$ s), d]	13.2 ± 11.1	11.7 ± 10.1	0.798
Total hospital stay [($\overline{x}\pm$ s), d]	36.6 ± 21.2	23.3 ± 17.2	0.032
Total length of PICU [($\overline{x}\pm$ s), d]	15.2 ± 12.2	13.4 ± 11.2	0.763
PEEP [($\overline{x}\pm$ s), cmH2O]	9.8 ± 2.6	10.6 ± 3.3	0.607
PIP [($\overline{x}\pm$ s), cmH2O]	26.3 ± 3.3	30.5 ± 5.6	0.018
OI ($\overline{x}\pm$ s)	16.2 ± 7.8	19.3 ± 11.7	0.494
CRP ($\overline{x}\pm$ s, mg/L)	139.3 ± 60.6	75.5 ± 55.6	0.001
PCT (n, ng/mL)	3.2 (1.5, 13.9)	1.2 (0.4, 7.3)	0.041
VIS (n %)			0.085
<50	10 (55.6%)	21 (77.8%)
50–100	3 (16.6%)	5 (18.5%)
>100	5 (27.8%)	1 (3.7%)
VIS (n)	6.3 (26.3, 105)	10 (0, 32.5)	0.045
CRRT therapy (n %)			0.694
Yes	4 (22.2%)	4 (14.8%)
No	14 (77.8%)	23 (85.2%)
Cause of ARDS (n %)			0.086
Pulmonary	11 (61.1%)	23 (85.2%)
Exogenous pulmonary	7 (38.9%)	4 (14.8%)
MODS (n %)
With MODS	8 (44.4%)	16 (59.3%)	0.329
Without MODS	10 (55.6%)	11 (40.7%)

PEEP, Positive end-expiratory pressure; PIP, Peak Inspiratory Pressure; OI, Oxygenation index; CRP, C Reactive Protein; PCT, Procalcitonin; VIS, vasoactive inotropic score; CRRT, continuous renal replacement therapy; ARDS, acute respiratory distress syndrome; MODS, multiple organ dysfunction syndrome.