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. 2021 Jul 8;8:705829. doi: 10.3389/fmed.2021.705829

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Copyright © 2021 Cheng, Zhao, Jiang, Kong and Sun.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Measurement and regionalized of the retinal vessels (RV) diameter were demonstrated. Using the Spectralis OCT + HRA system, a circular scan with a 3.4 mm diameter centered on the optic nerve was performed through natural pupils. Near-infrared reflectance images were obtained simultaneously. The retinal vessel (RV) diameter was measured as the maximum reflectance shadowing width on the retinal pigment epithelium layer. Using Spectralis software (Heidelberg Eye Explorer, version 1.0.10.0), scales (yellow bar) were drawn and measured. The sums of the overall parapapillary RV diameters, and the average parapapillary RNFLTs were determined for the entire region and for the T (315°-45°), TS (45°-90°), and TI sectors (270°-315°) individually.