TABLE 1.

Univariate and multivariate Cox analyses of the m6A-GSVS and routine clinicopathologic characteristics in patients with lung adenocarcinomas.

Characteristic	Univariate Cox analysis				Multivariate Cox analysis
	β	HR	HR (95%CI)	P value	β	HR	HR (95%CI)	P value
Gender
Male	ref.
Female	0.060	1.061	0.793–1.420	0.689
Age	0.009	1.009	0.994–1.024	0.259
Primary tumor (T)
T1–2	ref.
T3–4	0.861	2.366	1.622–3.451	0.000	0.671	1.956	1.281–2.986	0.002
Tx	1.284	3.611	0.887–14.693	0.073	1.135	3.112	0.411–23.557	0.272
Lymph nodes (N)
N0	ref.
N1–3	0.957	2.605	1.938–3.500	0.000	0.846	2.331	1.638–3.315	0.000
Nx/Not available	0.479	1.615	0.592–4.409	0.995	0.127	1.136	0.279–4.629	0.859
Metastases (M)
M0	ref.
M1	0.731	2.077	1.214–3.553	0.008	0.318	1.374	0.742–2.546	0.312
Mx/Not available	−0.174	0.841	0.587–1.204	0.344	−0.074	0.929	0.647–1.335	0.691
Pathological stage
I-II	ref.
III-IV	0.962	2.618	1.921–3.567	0.000	0.160	1.174	0.757–1.819	0.474
Not available	−0.370	0.691	0.170–2.800	0.604	−0.519	0.595	0.146–2.425	0.469
m6A GSVS	0.820	2.270	1.192–4.324	0.013	0.939	2.559	1.310–4.998	0.006

HR, hazard ratio; CI, confidence interval; ref., reference; m6A-GSVS, m6A-related gene set variation score. Bold values p represent <0.05.