Table 1.
Comparison of clinical and laboratory data at onset: Group A vs. Group B and prospective vs. retrospective cohort.
| Prospective cohort | Restrospective cohort | p-value | ||||||
|---|---|---|---|---|---|---|---|---|
| Total | Group A | Group B | Total | Group A vs. Group B | Adjusted (Holm's method) | Prospective vs. retrospective | Adjusted (Holm's method) | |
| (143 pts) | (100 pts) | (43 pts) | (144 pts) | |||||
| Clinical data | ||||||||
| Age (years) | 4.55 ± 2.7 | 4.73 ± 2.53 | 4.14 ± 3.06 | 4.75 ± 3.06 | 0.01 | 0,21 | 0.885 | 1 |
| Sex (Male) | 93 (65.0%) | 65 (65.0%) | 28 (65.1%) | 96 (66.7%) | 0.989 | 1 | 0.771 | 1 |
| Height (SDS) | −0.04 ± 0.87 | −0.08 ± 0.81 | 0.05 ± 1.01 | 0.02 ± 1.00 | 0.412 | 1 | 0.481 | 1 |
| Weight (SDS) | 0.46 ± 0.89 | 0.4 ± 0.91 | 0.64 ± 0.84 | 0.55 ± 1.03 | 0.082 | 1 | 0.171 | 1 |
| BMI (SDS) | 0.65 ± 0.93 | 0.60 ± 0.92 | 0.79 ± 0.95 | 0.72 ± 0.89 | 0.207 | 1 | 0.541 | 1 |
| sBP (SDS) | 1.07 ± 1.12 | 1.01 ± 1.05 | 1.23 ± 1.27 | 0.86 ± 1.14 | 0.294 | 1 | 0.083 | 1 |
| dBP (SDS) | 1.34 ± 0.88 | 1.28 ± 0.76 | 1.5 ± 1.12 | 1.13 ± 0.91 | 0.529 | 1 | 0.150 | 1 |
| SGA | 16/143 | 10/100 (10%) | 6/43 (13.8%) | 0.491 | 1 | |||
| Laboratory data | ||||||||
| Hemoglobin (g/dL) | 13.0 ± 1.2 | 13.08 ± 1.09 | 12.97 ± 1.34 | 13.3 ± 1.2 | 0.323 | 1 | 0.104 | 1 |
| Urea (mg/dL) | 29.3 ± 16.5 | 26.66 ± 13.25 | 35.26 ± 21.07 | 28.6 ± 13.2 | 0.01 | 0,21 | 0.936 | 1 |
| Creatinine (mg/dl) | 0.30 ± 0.15 | 0.29 ± 0.12 | 0.34 ± 0.21 | 0.35 ± 0.15 | 0.653 | 1 | 0.001 | 0.022 |
| Uricemia (mg/dL) | 4.23 ± 0.99 | 4.04 ± 0.93 | 4.65 ± 1.01 | 4.13 ± 1.09 | 0.004 | 0,088 | 0.546 | 1 |
| Total proteins (g/dL) | 4.23 ± 0.58 | 4.26 ± 0.59 | 4.18 ± 0.58 | 4.21 ± 0.67 | 0.323 | 1 | 0.734 | 1 |
| Albumin (g/dL) | 1.63 ± 0.50 | 1.64 ± 0.52 | 1.60 ± 0.46 | 1.40 ± 0.40 | 0.955 | 1 | 0.001 | 0.022 |
| Tot. cholesterol (mg/dL) | 403.7 ± 108.1 | 395.7 ± 108.05 | 421.09 ± 107.49 | 400.1 ± 102.1 | 0.049 | 0,784 | 0.665 | 1 |
| Triglycerides (mg/dL) | 197.20 ± 110.2 | 184.2 ± 92.12 | 225.86 ± 139.03 | 217.62 ± 138.5 | 0.074 | 1 | 0.331 | 1 |
| Na (mmol/L) | 136.8 ± 3.5 | 137.25 ± 3.54 | 135.84 ± 3.11 | 136.2 ± 3.4 | 0.03 | 0,522 | 0.240 | 1 |
| K (mmol/L) | 4.47 ± 0.50 | 4.42 ± 0.43 | 4.61 ± 0.52 | 4.51 ± 0.56 | 0.02 | 0,38 | 0.921 | 1 |
| Ca (mg/dL) | 8.18 ± 0.55 | 8.15 ± 0.61 | 8.24 ± 0.42 | 8.18 ± 0.70 | 0.439 | 1 | 0.652 | 1 |
| P (mg/dL) | 4.93 ± 0.82 | 4.84 ± 0.81 | 5.12 ± 0.82 | 5.08 ± 1.09 | 0.029 | 0,522 | 0.287 | 1 |
| uPr/uCr (mg/mg) | 13.39 ± 10.7 | 11.74 ± 9.41 | 17.44 ± 12.6 | 10.32 ± 7.22 | 0.002 | 0.046 | 0.056 | 1 |
| Proteinuria (g/L) | 9.32 ± 9.13 | 8.29 ± 8.27 | 11.91 ± 10.71 | 8.05 ± 8.17 | 0.088 | 1 | 0.230 | 1 |
| Microhematuria | 58 (40.6%) | 37 (37.0%) | 22 (51.2%) | 59 (41.0%) | 0.114 | 1 | 0.943 | 1 |
| Steroid response | ||||||||
| TTR (days) | 10.3 ± 7.8 | 14.8 ± 12.4 | 0.00025 | 0.00575 | ||||
Mean ± SD for numerical variables, number (%) for categorical variables. BMI, body mass index; sBP, systolic blood pressure; dBP, dyastolic blood pressure; SGA, small for gestational age. The red color values represent the significant values.