Table 1.
Summary of cell protection, channel inhibition, and antiviral activity of 34 compounds.
| Compound name | Channel inhibition (100 μM) | Cellular protection (10 μM) | Antiviral activity (inhibition%, 10 μM) |
|---|---|---|---|
| 2-Deoxy-D-glucose | - | 1.34 | <20 |
| Talazoparib | - | 1.43 | 20–40 |
| Veliparib | + | 1.34 | >40 |
| Carsalame | - | 1.13 | >40 |
| Gossypol-acetic acid | - | 1.41 | >40 |
| Salvianolic acid B | - | 1.39 | <20 |
| GW4869 | - | 1.29 | 20–40 |
| Wortmannin | + | 1.30 | >40 |
| Demethyl | - | 1.18 | >40 |
| COH29 | - | 1.28 | >40 |
| IPA-3 | - | 1.27 | <20 |
| BMS-626529 | - | 1.21 | <20 |
| AT101 | - | 1.36 | 20–40 |
| Quercetin | - | 1.26 | 20–40 |
| Kartogenin | - | 1.27 | 20–40 |
| Edoxaban | - | 1.35 | <20 |
| Rifamycin sodium | + | 1.21 | <20 |
| Midecamycin | + | 1.20 | <20 |
| Dihydroartemisinin | + | 1.37 | <20 |
| Proanthocyanidins | + | 1.92 | 20–40 |
| Artemisinin | + | 1.22 | 20–40 |
| Artesunate | - | 1.49 | <20 |
| Phenindione | - | 1.20 | <20 |
| Dihydroergotamine mesylate | + | 1.14 | <20 |
| Evans blue | - | 1.58 | <20 |
| Streptomycin sulfate | - | 1.18 | <20 |
| Nafronyl oxalate | + | 1.24 | <20 |
| Dimethyl fumarate | + | 1.14 | <20 |
| Valdecoxib | + | 1.37 | <20 |
| Chloropyramine hydrochloride | - | 1.36 | >40 |
| ABT-199 (GDC-0199) | - | 1.22 | 20-40 |
| Sapogenins Glycosides | - | 1.15 | <20 |
| Carbamazepine | - | 1.17 | <20 |
| Oxybutynin | - | 1.47 | <20 |
“+” means the inhibition of 2-E channels; “-” means no inhibition of 2-E channels.