TABLE 4.

CSF analysis results by tumor type and grade in dogs with glioma ⁵

Tumor type and grade a	Elevated TP concentration b	Elevated TNCC c	ACD d	Normal CSF a	Mean TP concentration and range (mg/dL)	Mean TNCC and range (cells/μL)	Differential cytology
LO (3)	1 (2)	1 (3)	1 (2)	1 (2)	23.3 (20‐26.5)	28 (1‐81)	Eosinophilic pleocytosis, 1 e
HO (13)	8 (11)	3 (13)	6 (11)	3 (11)	143.0 (10.1‐780)	38 (0‐460)	Increased percentage of neutrophils (62%), 1 f ; Mixed cell pleocytosis, 3 g
HA (4)	3 (4)	3 (4)	0 (4)	1 (4)	206.1 (22.5‐736)	15 (0‐27)	Mixed cell pleocytosis, 3
HU (3)	1 (2)	1 (3)	0 (2)	1 (2)	75.1 (20‐130.2)	10 (0‐27)	Neutrophilic pleocytosis, 1 h

Abbreviations: ACD, albuminocytologic dissociation; CSF, cerebrospinal fluid; HA, high‐grade astrocytoma; HO, high‐grade oligodendroglioma; HU, high‐grade undefined glioma; LO, low‐grade oligodendroglioma; TNCC, total nucleated cell count; TP, total protein.

^a Number of cases in which CSF information was available.

^b Number of cases with >25 mg/dL TP concentration (number of cases with available information).

^c Number of cases with >5 cells/μL (number of cases with available information).

^d Number of cases with >25 mg/dL TP concentration and <5 cells/μL (number of cases with available information).

^e Defined as CSF with >50% eosinophils.

^f Defined as CSF >2% nondegenerated neutrophils. ³⁵

^g Defined as CSF with a mixture of mostly lymphocytes and large mononuclear cells and >20% contribution of neutrophils and, occasionally, eosinophils. ³⁵

^h Defined as CSF with >75% neutrophils.