TABLE 1.
Detection of env gene expression by RT-PCR from 4070A in RG2 tumors from brain and systemic organs
| Tumors & Treatment |
|||
|---|---|---|---|
| Organs w/ Tumor | RCR-CD–Infected RG2 & PBS | RCR-CD–Infected RG2 & 5FC | RCR-CD–Pretransduced RG2 & 5FC |
| brain | + | + | + |
| lung | − | − | − |
| liver | − | − | − |
| spleen | − | − | − |
| kidney | − | − | − |
| bone marrow | − | − | − |
| upper GI (esophagus) | − | − | − |
| lower GI (intestine) | − | − | − |
| skin | − | − | − |
| testes | − | − | − |
No detectable virus was found outside the central nervous system. The env gene from 4070A was expressed inside the brain tumor only. + = present; − = absent.