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. 2021 Jul 21;4(7):e2116589. doi: 10.1001/jamanetworkopen.2021.16589

Table 2. Association Between Treatment With Electroconvulsive Therapy and Suicide Risk in an Adjusted Model Stratified by Age Group and Severity of Depressiona.

Variable aHR (95% CI) P value P value for interaction analyses Total suicide events
Age groups, y
18-44 1.22 (0.68-2.16) .51 Reference 75
45-64 0.54 (0.30-0.99) .05 .04b 76
≥65 0.30 (0.15-0.59) .001 .001b 59
Severity of depression
Moderate (F32.1, F33.1)c 0.93 (0.46-1.87) .84 Reference 75
Severe without psychosis (F32.2, F33.2) 0.65 (0.41-1.04) .07 .42d 99
Severe with psychosis (F32.3, F33.3) 0.20 (0.08-0.54) .001 .01d 36

Abbreviation: aHR, adjusted hazard ratio.

a

Cox regression model during 90 days of follow-up after date of admission, stratified by age group and severity of depression. Interactions analyses are reported in a separate column.

b

P values for interaction with 18-44 y.

c

Numbers represent International Statistical Classification of Diseases and Related Health Problems, Tenth Revision codes.

d

P values for interaction with moderate severity of depression.