TABLE 4.

Binding affinity value of Hydroxychloroquine, Cholroquine and Ivermectin against SARS-COV-2 targets.

SARS-CoV-2Protein target	Hydroxychloroquine (pubchem ID: 3652) binding affinity (kcal/mol)	Chloroquine (pubchem ID: 2719). Binding affinity (kcal/mol)	Ivermectin (pubchem ID: 6427057). Binding affinity (kcal/mol)
SARS-CoV-2MPro	−5.5	−4.9	−7.3
RdRp	−5.6	−5.4	−9.4
NSP3	−4.5	−4.2	−6.7
NSP9	−5.7	−5.2	−7.5
NSP16 - NSP10	−5.7	−5.3	−1.9
NSP15	−5.5	−5.4	−6.4
Spike glycoprotein	−5.3	−5.2	−8.2