TABLE 6.
Phytochemicals having strong interaction based on the top 10 hits screened for SARS-CoV-2targets.
| S. No | Compound name | Plant name | Protein targets |
|---|---|---|---|
| Acetoside | Clerodendrum serratum a | NSP3 | |
| Agathisflavone | Anacardium occidentale | SARS-CoV-2Mpro | |
| RdRp | |||
| NSP3 | |||
| Spike glycoprotein | |||
| Agnuside | Vitex negundo | SARS-CoV-2Mpro | |
| Spike glycoprotein | |||
| Amentoflavone | Mangifera indica | RdRp | |
| NSP9 | |||
| NSP3 | |||
| NSP10-NSP16 | |||
| Spike glycoprotein | |||
| Arjungenin | Terminalia chebula a | RdRp | |
| NSP15 | |||
| Arjunolic acid | Terminalia chebula a | NSP15 | |
| Beta-amyrin | Cissus quadrangularis | NSP15, spike glycoprotein | |
| Catechin 7-O-gallate | Camellia sinensis | RdRp | |
| NSP15 | |||
| NSP3 | |||
| Spike glycoprotein | |||
| Chlorogenin | Solanum torvum | SARS-CoV-2Mpro | |
| NSP9 | |||
| NSP10-NSP16 | |||
| Corilagin | Terminalia bellirica a , Terminalia chebula a | RdRp | |
| NSP10-NSP16 | |||
| Crategolic acid | Syzygium aromaticum a | NSP15 | |
| RdRp | |||
| Cyanin | Zingiber officinale a | SARS-CoV-2Mpro | |
| RdRp | |||
| Diosgenin | Solanum nigrum, Pedalium murex | NSP9 | |
| Emetine | FDA approved drug | NSP10-NSP16 | |
| Friedelin | Vitex negundo, Acorus calamus | NSP9 | |
| NSP15 | |||
| Hederagenin | Nigella sativa | NSP15 | |
| Ivermectin | FDA approved drug | RdRp | |
| NSP3 | |||
| Spike glycoprotein | |||
| Lupeol | Carica papaya and Azadirachta indica | SARS-CoV-2Mpro | |
| Lupeol acetate | Pedalium murex | NSP10-NSP16 | |
| Luteolin 7-O-(6''-malonylglucoside) | Vitex negundo | SARS-CoV-2Mpro | |
| NSP3 | |||
| Luteolin 7-O-beta-D-glucoside | Vitex negundo | SARS-CoV-2Mpro | |
| NSP3 | |||
| Luteolin-7-o-beta-d-glucopyranoside | Vitex negundo | NSP3 | |
| Nimbinene | Azadirachtaindica | Spike glycoprotein | |
| N-methylsolasodine | Solanum nigrum | NSP9 | |
| Oleanolic acid | Ocimum basilicum, Cyprus rotundus, Clerodendrum serratum a , Ocimum tenuiflorum | NSP15 | |
| Rubusic acid | Pedalium murex | SARS-CoV-2Mpro | |
| NSP3 | |||
| Solanocapsine | Solanum nigrum | SARS-CoV-2Mpro | |
| NSP9 | |||
| Solasodine | Solanum nigrum, Solanum torvum | NSP9 | |
| Spirostan-3-ol | Solanum nigrum | NSP9 | |
| NSP10-NSP16 | |||
| Taraxerol | Cissus quadrangularis | NSP9 | |
| Spike glycoprotein | |||
| Taraxerol acetate | Cissus quadrangularis | NSP3 | |
| NSP10-NSP16 | |||
| Triterpenoid | Abutilon indicum | NSP15 | |
| Ursolic-acid | Ocimum basilicum, Pedalium murex, Malus domestica, Ocimum tenuiflorum | NSP15 | |
| 5,7-Dihydroxy-4'-methoxy-8.3'-di-C-prenylflavanone | Azadirachta indica | NSP10-NSP16 | |
| 1,8-Dichloro-9,10-diphenylanthracene-9,10-diol | Carica papaya | Spike glycoprotein | |
| 3 O caffeoyltormentic acid | Antiviral compound | Spike glycoprotein | |
| 10-Methoxycamptothecin | Antiviral compound | NSP10-NSP16 | |
| 3.8'-biapigenin | Antiviral compounds | RdRp | |
| NSP10-NSP16 | |||
| 3-O-trans-caffeoyltormentic acid | Antiviral compound | SARSCoV-2 Mpro | |
| RdRp |
a
Kabasura kudineer-plant compounds.