Table 1.
Cohort Characteristics (N = 156)
| Characteristic | Value |
|---|---|
| Age, y | 64 ± 13 |
| Men | 71 (46) |
| Race | |
| White | 114 (73) |
| Black | 27 (17) |
| Hispanic | 9 (6) |
| Asian | 6 (4) |
| Ever smoked tobacco | 68 (44) |
| Pack-years if smoking | 24 ± 21 |
| Secondhand smoke exposure | 81 (52) |
| Family history of ILD | 19 (12) |
| Family history of CTD | 46 (29) |
| CTD diagnosis | 67 (43) |
| Autoimmune myositis | 25 (16) |
| Rheumatoid arthritis | 12 (8) |
| Mixed connective tissue disease | 12 (8) |
| Other | 18 (12) |
| Multidisciplinary diagnosis | |
| CTD-ILD | 66 (42) |
| IPF | 41 (26) |
| HP | 22 (14) |
| IPAF | 14 (9) |
| Unclassifiable | 4 (3) |
| COP | 3 (2) |
| CPFE | 3 (2) |
| PPFE | 2 (1) |
| Sarcoid | 1 (1) |
| Exposure | |
| Any | 101 (65) |
| Occupational | 59 (38) |
| Organic | 25 (16) |
| Metal | 21 (13) |
| Silica | 6 (4) |
| Domestic | 74 (47) |
| Mold | 39 (25) |
| Bird | 42 (27) |
| Hobby | 32 (21) |
| Gardening | 17 (11) |
| Woodworking | 13 (8) |
| Multiple (> 1) | 62 (40) |
Values are mean ± SD or No. (%). COP = cryptogenic organizing pneumonia; CPFE = combined pulmonary fibrosis emphysema; CTD = connective tissue disease; CTD-ILD = connective tissue disease-associated interstitial lung disease; HP = hypersensitivity pneumonitis; ILD = interstitial lung disease; IPAF = interstitial pneumonia with autoimmune features; IPF = idiopathic pulmonary fibrosis; PPFE = pleuroparenchymal fibroelastosis.