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. 2021 Feb 20;160(1):209–218. doi: 10.1016/j.chest.2021.02.026

Table 2.

Reported Exposures by Key Patient Characteristics

Sex Men (n = 71) Women (n = 85) OR (Men vs Women) 95% CI P Valuea
Any exposure 58 (82) 43 (51) 4.37 1.99-9.60 < .001b
Occupational exposure 47 (66) 12 (14) 10.14 4.50-22.83 < .001b
Mold 12 (17) 27 (32) 0.43 0.19-0.98 .05
Bird 22 (31) 20 (24) 1.45 0.67-3.12 .29
Hobby 21 (30) 11 (13) 2.92 1.23-6.94 .01b
Multiple exposures 40 (56) 22 (26) 3.70 1.78-7.66 < .001b
Race White (n = 114) Black (n = 27) Hispanic (n = 9) Asian (n = 6) OR (White vs Nonwhite) 95% CI P Valuec
Any exposure 78 (68) 14 (52) 5 (56) 4 (67) 1.44 0.67-3.11 .35
Occupational exposure 45 (39) 9 (33) 2 (22) 3 (50) 0.87 0.35-2.16 .68
Mold 30 (26) 7 (26) 1 (11) 1 (17) 1.52 0.63-3.63 .34
Bird 38 (33) 1 (4) 3 (33) 0 (0) 4.24 1.38-13.00 .01b
Hobby 29 (25) 3 (11) 0 (0) 0 (0) 3.93 1.11-13.89 .03
Multiple exposures 52 (46) 6 (22) 4 (44) 0 (0) 2.11 0.91-4.91 .08
Diagnosis IPF (n = 41) HP (n = 22) CTD (n = 66) IPAF (n = 14) Other (n = 13) OR (HP vs non-HP) 95% CI P Valuec
Any exposure 34 (83) 20 (91) 30 (45) 9 (64) 8 (62) 9.49 2.02-44.61 .004b
Occupational exposure 23 (56) 10 (45) 15 (23) 7 (50) 4 (31) 2.91 0.94-9.03 .06
Mold 10 (24) 12 (55) 11 (17) 3 (21) 3 (23) 4.29 1.65-11.18 .003b
Bird 19 (46) 10 (45) 8 (12) 2 (14) 3 (23) 2.75 1.05-7.18 .04
Hobby 18 (44) 8 (36) 1 (2) 4 (29) 1 (8) 3.35 1.17-9.54 .02
Multiple exposures 26 (63) 15 (68) 9 (14) 8 (57) 4 (31) 5.43 1.84-16.03 .002b

Values are No. (%) or as otherwise indicated. CTD = connective tissue disease; HP = hypersensitivity pneumonitis; IPAF = interstitial pneumonia with autoimmune features; IPF = idiopathic pulmonary fibrosis.

a

Adjusted for age and pack-years smoking.

b

Significant P value adjusting for multiple hypotheses.

c

Adjusted for age, sex, and pack-years smoking.