Table 3.
HRCT Features and Baseline Pulmonary Function by Exposure
| Variable |
Any Exposure |
Occupational Exposure |
Multiple Exposures |
||||||
|---|---|---|---|---|---|---|---|---|---|
| HRCT Scan (n = 141) | Yes (n = 93) | No (n = 48) | P Valuea | Yes (n = 55) | No (n = 86) | P Valuea | Yes (n = 57) | No (n = 84) | P Valuea |
| Lymphadenopathy | 52 (56) | 25 (52) | .73 | 34 (62) | 43 (50) | .74 | 33 (58) | 44 (52) | .98 |
| Honeycombing | 58 (62) | 23 (48) | .23 | 34 (62) | 47 (55) | .61 | 40 (70) | 41 (49) | .05 |
| Coronary artery calcification | 72 (77) | 31 (65) | .86 | 45 (82) | 58 (68) | .91 | 43 (75) | 60 (71) | .13 |
| Emphysema | 14 (15) | 10 (21) | .30 | 10 (18) | 14 (16) | .72 | 7 (12) | 17 (20) | .13 |
| CT UIP | 46 (49) | 17 (35) | .54 | 29 (53) | 34 (40) | .24 | 31 (54) | 32 (38) | .47 |
| PFTs (n = 153) | Yes (n = 98) | No (n = 55) | P Valuea | Yes (n = 57) | No (n = 96) | P Valuea | Yes (n = 59) | No (n = 94) | P Valuea |
|---|---|---|---|---|---|---|---|---|---|
| FVC % predicted | 63 ± 19 | 67 ± 19 | .25 | 62 ± 18 | 67 ± 19 | .08 | 63 ± 17 | 66 ± 19 | .47 |
| Dlco % predicted | 55 ± 23 | 55 ± 23 | .81 | 54 ± 22 | 56 ± 24 | .82 | 54 ± 21 | 56 ± 24 | .86 |
| FEV1/FVC ratio, % | 84 ± 9 | 83 ± 10 | .32 | 83 ± 10 | 84 ± 9 | .69 | 83 ± 10 | 83 ± 9 | .40 |
Values are mean ± SD, No. (%), or as otherwise indicated. Dlco = diffusing capacity of carbon monoxide; HRCT = high-resolution CT; PFT = pulmonary function tests; UIP = usual interstitial pneumonia.
a
Adjusted for age, sex, and pack-years smoking.