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Table 3.

Association of Postbronchodilator FEV1 to SVC Ratio of < 0.7 With Chest CT Scan Features in Smokers With Normal Spirometry Resultsa (n = 854)

Variable β (95% CI) P Value
% Emphysema 0.45 (0.09-0.82) .014
% Gas trapping 2.52 (0.59-4.44) .010
% PRMfSAD 2.78 (0.72-4.83) .0081

Each row represents a model. All models included the following covariates: age, sex, race, smoking status, and smoking pack-years at the enrollment. Data regarding % emphysema, % gas trapping, % PRMfSAD, and current smoking were missing in 7, 4, 96, and 9 participants, respectively. PRMfSAD = parametric response mapping functional small airways disease; SVC = slow vital capacity.

a

Normal spirometry results defined as postbronchodilator FEV1 ≥ 80% and postbronchodilator FEV1/FVC ≥ 0.7.