Table 3.
Association of Postbronchodilator FEV1 to SVC Ratio of < 0.7 With Chest CT Scan Features in Smokers With Normal Spirometry Resultsa (n = 854)
Variable | β (95% CI) | P Value |
---|---|---|
% Emphysema | 0.45 (0.09-0.82) | .014 |
% Gas trapping | 2.52 (0.59-4.44) | .010 |
% PRMfSAD | 2.78 (0.72-4.83) | .0081 |
Each row represents a model. All models included the following covariates: age, sex, race, smoking status, and smoking pack-years at the enrollment. Data regarding % emphysema, % gas trapping, % PRMfSAD, and current smoking were missing in 7, 4, 96, and 9 participants, respectively. PRMfSAD = parametric response mapping functional small airways disease; SVC = slow vital capacity.
Normal spirometry results defined as postbronchodilator FEV1 ≥ 80% and postbronchodilator FEV1/FVC ≥ 0.7.