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. 2021 Feb 18;160(1):219–230. doi: 10.1016/j.chest.2021.02.021

Table 3.

Selected Randomized Controlled Trials Documenting Benefit of Home Interventions in Asthma

Study Population Intervention Outcomes
Morgan et al,87 2004 Children with poorly controlled asthma and documented sensitivity to home allergens Visual inspection and dust collection
All participants receive allergen-impermeable bed covers and HEPA filtration vacuums
Child-specific interventions included HEPA air filters and pest control measures
Intervention reduced symptoms at 1- and 2-y follow-up time points
Evans et al,85 1999 Children with moderate or severe asthma Allergen-impermeable bed covers and education about minimizing exposure to tobacco smoke, pets, and pests
Social worker-administered global asthma intervention based on the Asthma Risk Assessment Tool
Intervention reduced symptom days and hospitalizations over a 2-y follow-up period
Kercsmar et al,86 2006 Children with symptomatic asthma living in a home with visible mold Control group education about home cleaning and asthma management
Intervention group also received home repairs aimed at remediation of water infiltration and mold (eg, HVAC maintenance)
Intervention reduced symptom days and exacerbations over 12 mo of follow-up

HEPA = high-efficiency particulate air; HVAC = heating, ventilation, and air conditioning.