Skip to main content
. 2021 Jul 8;8:658029. doi: 10.3389/fmolb.2021.658029

FIGURE 2.

FIGURE 2

(A) Crystal structures of rotavirus VP8*s. Phylogenetic analysis of VP8*s of 35 RV P genotypes (circular dendrogram) was conducted by MEGA6 using the neighbor-joining method. The crystal structures of VP8*s in complex with glycans are presented. P[3], Rhesus rotavirus RRV in complex with Sia, rainbow, PDB ID: 1KQR. P[7], CRW-7 in complex with sia, teal, PDB ID: 3TAY. P[14], human rotavirus HAL1166 in complex with A-type HBGA, cyan, PDB ID: 4DRV. P[9], human rotavirus K8 in complex with A-type HBGA, Aquamarine, PDB ID: 5CB7. P[11], human neonatal rotavirus N155 in complex with type II tetrasaccharide LNnT, salmon, PDB ID: 4YG0. P[11], bovine rotavirus B223 in complex with type II tetrasaccharide LNnT, lightpink, PDB ID: 4YG6. P[6], human rotavirus RV3 in complex with LNFP1, skyblue, PDB ID: 6OAI. P[19], human rotavirus MC345 in complex with LNT, green, PDB ID: 5YMT. P[4], human rotavirus DS-1 in complex with LNFP1, warmpink, PDB ID: 5VX5. P[8], human rotavirus Rotateq in complex with LNFP1, yellow, PDB ID: 6K2O. (B) Phylogenetic analysis of VP8*s of 50 RV P genotypes (circular dendrogram) was conducted by MEGA6 using the neighbor-joining method. The GeneBank number: P[1]NCDV, AB119636; P[2]SA11, NC_011510; P[3]RRV, LC438917; P[4]DS1, CAD62680; P[5], GU565055; P[6]ST3, L33895; P[6]RV3, ADD31861; P[7]CRW-8, UniProtKB:P0C6Y8; P[8]Rotateq, GU565044; P[8]Wa, L34161; P[9]K8, D90260; P[10]69M, M60600; P[11]HRV, UniProtKB: B6RGK2; P[11]BRV, M92986; P[12]H2, D13397; P[13]A46, AY050274; P[14]HAL1166, L20875; P[15]LLR, JQ013506; P[16], KJ477163; P[17]993-83, D16352; P[18]L338, D13399; P[19]HumanMc345, D38054; P[20]EHP, U08424; P[21]HG18, AF237665; P[22]160-1, AF526374; P[23]A34, AY174094; P[24] TUCH, AY596189; P[25], KC140588; P[26], DQ061053; P[27], DQ242615; P28human, EU805773; P[29], AB454420; P[30], FJ169856; P[31], EU486962; P[32], FJ492835; P[33], AB513836; P[34], AB571047; P[35], EU486958; P[36], AB971763; P[37], JX204814; P[38], LC088110; P[39], LC088221; P[40], KT935478; P[41], KU128895; P[42], KX268757; P[43], KX268779; P[45], KU243630; P[46], KU243621; P[47], KX268790; P[48], KX814933; P[49], PKY905314; P[50], KY971955; P[51], MH285840.