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. 2021 Jul 8;8:658029. doi: 10.3389/fmolb.2021.658029

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Copyright © 2021 Sun, Li and Duan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Structural analysis of the VP8* structures. Superimposition of the VP8* structures to compare the width of the cleft between two β-sheets (βH and βK). The width of the cleft in VP8*s of different P genotype are measured. P[3], P[7], P[9], P[14], P[11], P[19], P[4], P[6], P[8] VP8*s are colored as described in Figure.2A and P[25] is colored deep green (PDB ID: 7C8P). (B) The structural based sequence alignment was constructed using Clustal Omega and displayed with the ESPript 3.0 (https://espript.ibcp.fr/ESPript/cgi-bin/ESPript.cgi). Residue 101 and 136 were pointed with red arrows.