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. 2021 Jul 22;14:280. doi: 10.1186/s13104-021-05688-4

Table 2.

Associations between chronic stress or sleeping habits and GI symptoms during the past 2 weeks

No symptoms N = 2189 (82.7%) Symptoms N = 459 (17.3%) Crude OR 95% CI P-value Adjusted OR 95% CI P-value
Chronic stress 1 year
 No (reference) 59.6 43.6 1.000 1.000
 Yes 40.1 56.2 1.918 (1.565–2.351)  < 0.001 1.510 (1.201–1.897)  < 0.001
 Missing 0.4 0.2
Chronic stress 5 years
 No (reference) 64.1 52.5 1.000 1.000
 Yes 35.3 46.4 1.604 (1.308–1.967)  < 0.001 1.435 (1.137–1.812) 0.002
 Missing 0.6 1.1
Sleeping quality
 Very good (reference) 27.9 23.1 1.000 1.000
 Good 35.4 32.0 1.092 (0.832–1.432) 0.525 1.180 (0.874–1.547) 0.279
 Average 26.4 31.4 1.439 (1.092–1.895) 0.010 1.349 (1.082–1.941) 0.059
 Bad 8.9 11.3 1.545 (1.068–2.235) 0.021 1.231 (1.007–2.243) 0.361
 Very bad 1.1 2.0 2.256 (1.016–5.008) 0.046 1.983 (1.040–5.389) 0.170
 Missing 0.4 0.2
Sleeping onset difficulty
 Never or rarely (reference) 44.4 38.6 1.000 1.000
 < 1 per week 29.7 27.0 1.048 (0.816–1.345) 0.715 0.895 (0.676–1.185) 0.439
 1–2 per week 16.6 19.6 1.362 (1.028–1.803) 0.031 1.228 (0.893–1.688) 0.207
 3–6 per week 5.1 6.8 1.520 (0.990–2.334) 0.056 1.207 (0.731–1.922) 0.462
 Almost every night 3.7 7.6 2.344 (1.529–3.592)  < 0.001 1.680 (0.984–2.870) 0.057
 Missing 0.5 0.4
Sleeping hours per day
  ≤ 5 (reference) 6.2 7.6 1.000 1.000
 6 22.8 23.5 0.849 (0.555–1.299) 0.450 0.815 (0.522–1.273) 0.369
 7 44.5 38.1 0.703 (0.469–1.053) 0.087 0.683 (0.446–1.047) 0.080
 8 21.0 22.4 0.878 (0.572–1.348) 0.553 0.826 (0.524–1.300) 0.408
 9 4.3 6.5 1.249 (0.718–2.174) 0.431 0.942 (0.505–1.757) 0.850
  ≥ 10 0.8 1.5 1.522 (0.589–3.931) 0.385 0.992 (0.332–2.963) 0.988
 Missing 0.4 0.2
Wake-up frequency
 Never or rarely (reference) 31.2 25.1 1.000 1.000
  < 1 per week 23.4 24.0 1.273 (0.957–1.694) 0.097 1.381 (1.027–1.871) 0.046
 1–2 per week 18.5 19.8 1.334 (0.987–1.804) 0.060 1.352 (0.964–1.835) 0.081
 3–6 per week 12.3 16.1 1.628 (1.177–2.251) 0.003 1.679 (1.144–2.279) 0.006
 Almost every night 14.1 14.4 1.273 (0.914–1.772) 0.154 1.060 (0.814–1.681) 0.781
 Missing 0.5 0.7

GI, Gastrointestinal. OR, Odds Ratio. CI, Confidence Interval. Logistic regression adjusted for age, sex, occupation, and smoking. Values are presented as percentages and OR and 95% CI. P-values < 0.05 was considered statistically significant