Table 3.
Changes in neurological, psychological and cognitive scores of patients with ALS evaluated at baseline and follow-up.
| Patients T1 | Patients T2 | p-value | |
|---|---|---|---|
| ALSFRS (n = 17) | 40.1 ± 4.6 | 29.7 ± 1.6 | <0.001 |
| Norris scale (n = 17) | 35.1 ± 6.5 | 29.1 ± 12.4 | <0.001 |
| MRC (n = 17) | 102.3 ± 17.1 | 81.2 ± 28.8 | <0.001 |
| BDI (/39) (n = 17) | 3.3 ± 2.6 | 4.0 ± 4.5 | 0.5 |
| STAI-Y 1 (/80) (n = 17) | 34.2 ± 10.5 | 31.52 ± 9.7 | 0.1 |
| STAI-Y 2 (/80) (n = 17) | 34.8 ± 9.64 | 37.6 ± 11 | 0.4 |
| TMT B-A (s) (n = 12) | 62.0 ± 58.1 | 53.75 ± 38.1 | 0.9 |
| Animal VF index (n = 16) | 3.6 ± 1.1 | 3.7 ± 1.3 | 0.8 |
| Letter VF index (n = 16) | 6.6 ± 2.2 | 6.1 ± 2.0 | 0.7 |
| HSCT (n = 16) | 9.7 ± 2.4 | 5.2 ± 2.9 | 0.008 |
| LN-sequencing (n = 10) | 9.0 ± 3.9 | 9.6 ± 4.2 | 0.7 |
| FET-eyes be (n = 21) | 6.0 ± 1.2 | 6.0 ± 1.8 | 0.9 |
| FET-eyes ce (n = 21) | 4.8 ± 1.6 | 5.0 ± 1.8 | 0.7 |
| FET-face be (n = 21) | 7.0 ± 1.4 | 6.9 ± 1.8 | 0.9 |
| FET-face ce (n = 21) | 5.1 ± 1.6 | 4.9 ± 2.0 | 0.7 |
Values are means ± SD. ALSFRS, ALS Functional Rating Scale; MRC, Medical Research Council Muscle Strength Scale; BDI, Beck Depression Inventory; STAI-Y, Spielberger State and Trait Anxiety Inventory; 1, State; 2, Trait; TMT, Trail Making Test; VF, Verbal Fluency; HSCT, Hayling Sentence Completion Test; LN sequencing, Letter-Number Sequencing task; FET, Face Eyes Test; be, basis emotions; ce, complex emotions. Significance set at p < 0.05.