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. 2021 Jul 8;12:650216. doi: 10.3389/fphar.2021.650216

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Copyright © 2021 Xian, Li, Zhang, Li, Zhu, Li, Tan, Lin, Li and Pan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of GL-pp on the diversity and the significantly altered taxa of gut microbiota in mice with B16-F10-luc-G5 and SF. The α-diversity analysis including observed species (A), Shannon Index (B), Chao1 Index (C), ACE Index (D), and Simpson Index (E) is shown. The NMDS analysis results are shown in (F). The relative abundance of significantly altered taxa, including genus Bacteroides (G), genus Parvibacter (H), family Christensenellaceae (I), genus Desulfovibrio (J), and genus Odoribacter (K) in the Tumor, T + SF, and GL-pp groups are shown in (G–K). n = 3. Results are shown as mean ± SD. ^# p < 0.05 compared with the Tumor group; ^△ p < 0.05 compared with the T + SF group.