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. 2021 Jul 22;40:238. doi: 10.1186/s13046-021-02045-y

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — DNM2-dependent processes in tumor cells. AHI-1: Abelson helper integration site-1. BCR-ABL: product of the BCR-ABL fusion gene. Cort: Cortactin. DNM2: Dynamin 2. FasL: Fas Ligand. FBP17: Formin Binding Protein 17. HIF1: hypoxia-induced factor 1. IL-7: interleukin 7. IL-24: interleukin 24. MAPK: mitogen-activated protein kinase. MT1-MMP: membrane type 1 matrix metalloproteinase. P: phosphorylated residue in DNM2. PRL: prolactin. ROS: reactive oxygen species. SFK: Src-family kinase. SHP2: tyrosine-protein phosphatase non-receptor type 11. STAT3: signal transducer and activator of transcription 3. The miR199a and miR638 are both produced from the DNM2 gene. The figure was built using the Servier medical art database