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. 2021 Jul 22;12:413. doi: 10.1186/s13287-021-02480-w

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — The expression profiles of DE-miRNAs in OM-MSCs under hypoxic and normoxic conditions. A Hierarchical clustering was performed on differentially expressed microRNAs between hypoxic OM-MSCs and normoxia OM-MSCs. The results were standardized by log(value+1). B Expression of selected OM-MSCs miRNAs was verified by quantitative real-time PCR. Data are expressed as the mean ± SEM (n = 3) (^*P <0.05, ^**P <0.01, ^***P <0.001, ns. no significance)