Table 3.
MVMR analysis results
| Lung function measure | Condition | No SNPs (trait/condition) | Cognitive function | |
|---|---|---|---|---|
| Beta (SE) | p-value | |||
| FEV1 | None | 298/0 | − 0.06 (0.03) | < 0.001 |
| FEV1 | Height | 212/299 | − 0.03 (0.03) | 0.29 |
| FEV1 | BMI | 180/629 | − 0.07 (0.03) | 0.03 |
| FEV1 | Educational attainment | 274/32 | − 0.03 (0.03) | 0.33 |
| FVC | None | 381/0 | − 0.06 (0.01) | < 0.001 |
| FVC | Height | 278/314 | − 0.01 (0.03) | 0.62 |
| FVC | BMI | 224/595 | − 0.05 (0.02) | 0.004 |
| FVC | Educational attainment | 335/31 | − 0.01 (0.02) | 0.35 |
Effect of decreasing Lung function trait on cognitive function with and without conditioning for covariates
Negative beta indicates decreasing cognitive function
SE, standard error