Table 6.
Subgroup analysis for pregnancy outcomes according to TGAb/TPOAb.
| Outcomes | TGAb+ TPOAb+ (N=371) | TGAb+ TPOAb- (N=244) | TGAb- TPOAb+ (N=163) | TGAb- TPOAb- (N=778) | P values |
|---|---|---|---|---|---|
| Clinical pregnancya, No. (%) | 160/371 (43.1) | 112/244 (45.9) | 72/163 (44.2) | 351/778 (45.1) | 0.900 |
| Miscarriageb, No. (%) | 24/160 (15.0) | 16/112 (14.3) | 10/72 (13.9) | 50/351 (14.2) | 0.995 |
| Live birthc, No. (%) | 136/371 (36.7) | 96/244 (39.3) | 62/163 (38.0) | 301/778 (38.7) | 0.899 |
| Preterm deliveryd, No. (%) | 22/136 (16.2) | 12/96 (12.5) | 13/62 (21.0) | 47/301 (15.6) | 0.562 |
| Birth weight-g | |||||
| Singleton | 3400 (3100-3600) | 3400 (302.5-3650) | 3300 (3000-3500) | 3400 (3115-3650) | 0.343 |
| Twin | 2500 (2250-2800) | 2425 (2160-2675) | 2500 (2052.5-2715) | 2650 (2300-2900) | 0.013 |
TGAb, thyroglobulin antibody; TPOAb, thyroid peroxidase antibody.
aClinical pregnancy was defined as at least one gestational sac in the uterus at 35 days after embryo transfer, as identified on ultrasonography.
bMiscarriage was defined as loss of clinical pregnancy before 28 weeks gestation.
cLive birth was defined as the delivery of at least one survived newborn, irrespective of gestation duration.
dPreterm delivery was defined as the delivery of a living fetus before 37 weeks.