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. 2021 Jul 8;12:671595. doi: 10.3389/fimmu.2021.671595

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Copyright © 2021 Chen, Wei, Wu, Fan and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CAFs have a positive or negative interaction with immune cells via regulating various cytokines and chemokines. DC, dendritic cell; Treg cell, regulatory T cell; MDSC, myeloid‐derived suppressor cell; TGF‐β, transforming growth factor‐β; SDF-1, stromal-derived growth factor-1.