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IL-6 protein production in response to non-selective, Epac selective, or PKA selective cAMP analogs. BSMC were treated with the indicated concentration of either 8-Br-cAMP (non-selective), 8-CPT-2Me-cAMP (Epac selective), or 6-Bnz-cAMP (PKA selective) for 24 h and IL-6 in culture supernatant was measured by ELISA. Dashed line represents vehicle. Mean ± SEM, n=3–4 * indicates p<.05 compared to vehicle
