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. 2021 Jul 8;9:715674. doi: 10.3389/fcell.2021.715674

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Copyright © 2021 Zhou, Zhou, Shi, Guan, Zhu, Hou and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Expression of CD34/CD276 and m6A modification in CRC. (A) Peak statistics of clinical sequencing samples. (B) Compared with paracancerous tissues, the expression of CD276 was up-regulated in CRC tissue (P < 0.05), while the expression of CD34 did not significantly change (P > 0.05). (C) Difference m6A peak Volcano map. (D) Difference m6A peak calling. (E,F) CD34/CD276 is down-regulated m6A peak immune genes in CRC.