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. 2021 Jul 8;9:715674. doi: 10.3389/fcell.2021.715674

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Copyright © 2021 Zhou, Zhou, Shi, Guan, Zhu, Hou and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Clustering and survival analysis based on TCGA database. (A–C) The results of consistent cluster matrix, cumulative distribution function curve, and relative change of area under the curve showed that the expression of CD34/CD276 could be divided into two types of CRC samples. (D) K-M survival curve showed that patients with Cluster1 showed higher survival ability than those with Cluster2 (P < 0.05). (E) Compared with Cluster1, the expression of CD34/CD276 was up-regulated in Cluster2 (***P < 0.001).