Table 1. Optimization of the Reaction Conditions^a.

change in reaction conditions	yieldb
none	75%
Mn instead of Zn	n.o.
TDAE instead of Zn	n.o.
toluene instead of DMF	20%
no catalyst	n.o.
NiBr2 + phen instead of PdCl2(amphos)2	n.o.
PdCl2 instead of PdCl2(amphos)2	<5%
PdCl2(dppf) instead of PdCl2(amphos)2	20%
10 mol % PdCl2 + 30 mol % L2 instead of PdCl2(amphos)2	5%
no pyridine	66%

^aReactions were carried out on a 0.1 mmol scale.

^bYields were determined by ¹H NMR spectroscopy with mesitylene as the internal standard. TDAE = tetrakis(dimethylamino)ethylene. n.o. = not observed.