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. 2021 Jul 22;16(7):e0255018. doi: 10.1371/journal.pone.0255018

Table 4. Descriptive statistics for physiological outcomes and questionnaire responses at baseline, pre-intervention, and post-intervention (N = 20).

Measure Baseline (Week 0) Pre-Intervention (Week 12) Post-Intervention (Week 24) ICC^ (3,1) Effect Size^^ (d)
Physiological Outcomes:
Body Weight (kg) 72.3 ± 10.1 72.0 ± 9.5 72.2 ± 9.8 0.98 -0.01
Body Fat Percentage (%) 38.8 ± 5.8 38.7 ± 5.9 37.8 ± 5.7 0.99 0.67
Lean Body Mass (kg) 42.8 ± 8.4 42.7 ± 7.9 43.5 ± 8.1 0.99 0.63
Fat Mass (kg) 26.8 ± 4.3 26.6 ± 4.5 26.2 ± 4.5 0.96 0.21
Systolic Blood Pressure (mmHg) 121.6 ± 18.9 121.1 ± 15.0 117.2 ± 14.9 0.79 -0.04
Diastolic Blood Pressure (mmHg) 63.4 ± 10.4 64.2 ± 10.0 64.5 ± 10.9 0.77 -0.14
Heart Rate (bpm) 65.7 ± 9.9 65.6 ± 11.1 64.5 ± 10.6 0.77 -0.01
Total Body Strength (kg) 307.1 ± 141.3 299.5 ± 140.6 452.2 ± 162.6 0.99 3.86
 • Lower Body Strength (kg) 207.6 ± 106.1 202.6 ± 106.1 319.9 ± 125.3 0.99 3.73
 • Upper Body Strength (kg) 99.5 ± 37.4 96.8 ± 36.5 132.3 ± 40.9 0.98 3.37
Margaria Power (W) 362.2 ± 103.2 366.8 ± 101.6 417.2 ± 112.0 0.97 1.59
Timed Up and Go (sec) 5.9 ± 0.5 6.1 ± 0.6 5.4 ± 0.5 0.67 -1.98
Y-Balance## (cm) 396.4 ± 38.7 407.7 ± 37.3 430.5 ± 38.3 0.59 0.55
Habitual Gait Speed (m/sec) 1.4 ± 0.2* 1.4 ± 0.2* 1.5 ± 0.2* 0.68 0.01*
Questionnaire Responses:
PSQI Score 4.0 ± 2.8* 5.0 ± 3.0* 3.5 ± 1.75* 0.84 -0.39*
ISEL Score 15.0 ± 2.0* 14.3 ± 3.5* 15.0 ± 2.3* 0.81 0.69*
SF-36 Physical Functioning 95.0 ± 13.8* 92.5 20.0* 95.0 10.0* 0.53 0.47*
SF-36 Limitations Due to Physical Health 100.0 ± 18.8* 100.0 ± 25.0* 100.0 ± 0.0* 0.16 0.27*
SF-36 Limitations Due to Emotional Problems 100.0 ± 24.9* 100.0 ± 24.8* 100.0 ± 0.0* 0.10 0.30*
SF-36 Energy/Fatigue 76.0 ± 9.8 76.8 ± 10.6 79.3 ± 10.4 0.56 0.19
SF-36 Emotional Well-Being 88.0 ± 8.0* 88.0 ± 15.0* 90.0 ± 8.0* 0.77 0.26*
SF-36 Social Functioning 100.0 ± 12.5* 100.0 ± 0.0* 100.0 ± 0.0* 0.66 -0.24*
SF-36 Pain 90.0 ± 28.1* 90.0 ± 30.0* 90.0 ± 17.4* 0.72 0.13*
SF-36 General Health 77.8 ± 12.3 80.3 ± 12.5 85.3 ± 10.1 0.46 0.26

The control period 12-week test-retest reliability was important since this study was a single group clinical trial. No changes were observed from baseline to pre-intervention. The effects of the 12-week periodized RT intervention are evident via changes from pre- to post-intervention and calculated effect sizes. Mean ± SD.

^Two-way mixed intraclass correlation coefficient (ICC) with absolute agreement calculated using baseline and pre-intervention data.

^^Adapted Cohen’s d effect size calculated by subtracting the mean changes from pre- to post-intervention by the mean changes from baseline to pre-intervention and dividing the average standard deviation of those changes.

*Median ± IQR and matched-pairs rank-biserial effect size calculated on the changes from pre- to post-intervention versus changes from baseline to pre-intervention.

##Four participants were not able to perform all six reach directions at baseline and/or pre-intervention, so their data were excluded from analyses (N = 16).

PSQI = Pittsburgh Sleep Quality Index. Lower scores indicate better sleep quality, scores ≥ 5 are classified as clinically poor sleep quality.

ISEL = International Support Evaluation List. Higher scores indicate greater social support, up to a maximum of 16.

SF-36 = Short Form-36. Higher scores indicate greater health-related quality of life, up to a maximum of 100.