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. 2021 Jul 22;16(7):e0254374. doi: 10.1371/journal.pone.0254374

Fig 3. Pathway enrichment analysis from disease signatures (COVID-19 versus mock) in epithelial cell lines infected by SARS-CoV-2.

Fig 3

The top 40 most significantly dysregulated immunological canonical pathways in either the Calu-3 (yellow) and NHBE (brown) infected cell lines are represented in a radar plot according to -log (p-value). Pathway enrichment z-scores, based on fold change direction, represent predicted up-regulation (green dots) or down-regulation (blue dots) for positive or negative values, respectively.