FIGURE 6.

Concentration dependence of inhibition. To gain information about half-maximum inhibiting concentrations (IC₅₀), IV-ramps were recorded at several concentrations of inhibitor. (A) Open circle: control currents (pRK5); open square: currents induced by E protein expression in the absence of inhibitor; red: currents at 2 nM of inhibitor, except Rim (1 nM) and HMA (0.5 nM); blue: currents at 10 nM of inhibitor except Rim and HMA (5 nM). (B) Concentration-response curves constructed from a non-linear fit of data shown in panel (A). Left panel: black squares – Rim; blue circles – Ama; pink triangles – HMA; right panel: black square – Api; red circle – EGCG; purple up triangle – Gen; blue down triangle – Kae; turquoise diamond – Que; pink plus – Res. (C) Summary of IC₅₀ values.