Table 3.
Humorally mediated immune reactions
Case # | Sex | Age | Biopsy | Diagnosis | Outcome | |
---|---|---|---|---|---|---|
LCV | LCV 1 | W | 49 | N/A | Moderately severe leukocytoclastic vasculitis in association with significant complement activation likely representing an Arthus type III immune complex reaction but potentially with an underlying SARS-CoV-2–associated complement-driven microangiopathy. | Oxygen saturation while at the hospital remained at 100%. Gradually convalesced at home without any serious complications. |
LCV 2 | M | 72 | Right thigh | COVID-19 associated low-grade lymphocytic vasculitis and leukocytoclastic vasculitis in the setting of a robust type I interferon immune response reflective of effective interferon-driven cellular and antibody-triggered immunity to SARS-CoV-2. | Recovered | |
LCV 3 | M | 77 | Left calf; Right thigh | Iga-associated Vasculitis/infection-triggered Henoch-Schonlein Purpura. | Recovered | |
LCV 4 | M | 59 | Left arm | Urticarial Vasculitis | Recovered | |
LCV 5 | F | 55 | Right leg | Bullous LCV | Recovered |
COVID-19, coronavirus disease 2019; F, female; LCV, leukocytoclastic vasculitis; M, male; N/A,; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.