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. 2021 Jul 22;39(6):934–965. doi: 10.1016/j.clindermatol.2021.07.001

Table 3.

Humorally mediated immune reactions

Case # Sex Age Biopsy Diagnosis Outcome
LCV LCV 1 W 49 N/A Moderately severe leukocytoclastic vasculitis in association with significant complement activation likely representing an Arthus type III immune complex reaction but potentially with an underlying SARS-CoV-2–associated complement-driven microangiopathy. Oxygen saturation while at the hospital remained at 100%. Gradually convalesced at home without any serious complications.
LCV 2 M 72 Right thigh COVID-19 associated low-grade lymphocytic vasculitis and leukocytoclastic vasculitis in the setting of a robust type I interferon immune response reflective of effective interferon-driven cellular and antibody-triggered immunity to SARS-CoV-2. Recovered
LCV 3 M 77 Left calf; Right thigh Iga-associated Vasculitis/infection-triggered Henoch-Schonlein Purpura. Recovered
LCV 4 M 59 Left arm Urticarial Vasculitis Recovered
LCV 5 F 55 Right leg Bullous LCV Recovered

COVID-19, coronavirus disease 2019; F, female; LCV, leukocytoclastic vasculitis; M, male; N/A,; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.