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. 2021 Jul 8;11:672797. doi: 10.3389/fonc.2021.672797

Table 3.

Results of the performance indicators on the quality of metastatic melanoma care – Univariate Analysis.

Long-term outcomes Advanced Melanoma:IIIB-IIIC (unresectable), IV
Events1 (n) DOD/DEAD Median MSS (95% CI)
Melanoma-specific Survival (MSS) overall 314/353 47 (41-53)
Melanoma-specific Survival (MSS) of pts. with local treatment 132/147 42 (35-48)
Melanoma-specific Survival (MSS) of pts. with chemotherapy 151/163 33 (27-38)
Melanoma-specific Survival (MSS) of pts. with immunotherapy 126/137 50 (43-57)
MSS Immunotherapy: ANTI-PD-1 (Nivolumab/Pebrolizumab) 17/18 70 (39-101)
MSS Immunotherapy: ANTI-CTLA4 (Ipilimumab) 94/104 47 (37-56)
MSS Immunotherapy: ANTI-PD-1+ANTI-CTLA4 15/15 58 (26-90)
Melanoma-specific Survival (MSS) of pts. with target therapy 129/147 44 (38-50)
MSS BRAFi: vemurafenib/dabrafenib 91/107 40 (34-45)
MSS BRAFI+MEKI: cobimetinib/trametinib 38/40 55 (49-61)

1Event: number of deaths of the disease (DOD)/number of deaths for all causes (DEAD).