Table 2.

A list of used abbreviations and their explanations.

Abbreviation	Explanation
MS	Multiple sclerosis
ON	Optic neuritis
OCT	Optical coherence tomography
CNS	Central nervous system
LSI	Layer-stacked images
MS-ON	Multiple sclerosis with optic neuritis
MS-None ON	Multiple sclerosis without optic neuritis
MRI	Magnetic resonance imaging
RNFL	Retinal nerve fiber layer
GLCM	Grey-level cooccurrence matrix
HC	Health control
LBP	Local binary pattern
LDP	Local directional pattern
LOOP	Local optimal oriented pattern
SVM	Support vector machine
LDA	Linear discriminant analysis
FD	Fractal dimension
LS image	Layer-stacked image