Table 13.

Effect of topical application of ointment prepared from solvent fractions of 80% hydromethanolic leaf crude extract of B. abyssinica on period of epithelization on excision wound model in mice.

Treatment	Epithelization period in days	Percentage reduction in period epithelization
Simple ointment	18.67 ± 0.33	0.00
Aqueous fraction 5% (w/w) ointment	13.67 ± 0.21adefg(3)	26.78
Aqueous fraction 10% (w/w) ointment	13.50 ± 0.34adefg(3)	27.69
Chloroform fraction 5% (w/w) ointment	15.83 ± 0.40abch(3)fg(1)	15.21
Chloroform fraction 10% (w/w) ointment	15.67 ± 0.33abch(3)f2g1	16.07
Hexane fraction 5% (w/w) ointment	17.33 ± 0.21ad(1)bch(3)e2	7.18
Hexane fraction 10% (w/w) ointment	17.17 ± 0.17ade(1)bch(3)	8.03
Nitrofurazone 0.2% (w/v) ointment	13.50 ± 0.22adefg(3)	27.69

Data are expressed as mean ± SEM; n = 6; a, compared with simple ointment; b, compared with 5% aqueous fraction; c, compared with 10% aqueous fraction; d, compared with 5% chloroform fraction; e, compared with 10% chloroform fraction; f, compared with 5% hexane fraction; g, compared with 10% hexane fraction; h, compared with nitrofurazone 0.2% ointment; 1, p < 0.05; 2, p < 0.01; 3, p < 0.001.