Table 3.

Effect of topical application of ointment prepared from 80% hydromethanolic leaf crude extract of B. abyssinica on wound area (mm²) in excision wound model.

Ointment	Day 4	Day 6	Day 8	Day 10	Day 12	Day 14	Day 16
SOB	236.00 ± 4.62	175.67 ± 4.77	132.17 ± 2.97	109.50 ± 2.86	76.33 ± 1.89	44.83 ± 1.82	24.00 ± 1.67
HCEO 5% w/w	218.17 ± 3.48a1	158.67 ± 3.86a2	115.67 ± 3.61a2c3d3	57.33 ± 2.92a3c3d3	24.50 ± 0.99a3c3d3	7.67 ± 0.49a3c2d2	1.17 ± 0.54a3
HCEO 10% w/w	209.33 ± 4.12a2	146.00 ± 3.08a3	89.50 ± 1.84a3b3	39.17 ± 0.95a3b3	14.83 ± 0.98a3b3	1.67 ± 0.56a3b2	0.00 ± 0.00a3
NO 0.2% w/v	210.83 ± 3.64a2	144.83 ± 3.45a3	92.67 ± 2.04a3b3	40.67 ± 1.61a3b3	16.00 ± 0.73a3b3	1.83 ± 0.65a3b2	0.00 ± 0.00a3

Data are expressed as mean ± SEM; n = 6, a, compared with simple ointment; b, compared with crude methanolic extract 5% (w/w); c, compared with crude methanolic extract 10% (w/w) ointment; d, compared with nitrofurazone 0.2%(w/v) ointment. 1, p < 0.05, 2, p < 0.01, and 3, p < 0.001. SOB, simple ointment base; HCEO, hydromethanolic crude extract of B. abyssinica leaves; NO, nitrofurazone ointment.