Table 4.

Effect of topical application of ointment prepared from 80% hydromethanolic leaves crude extract of B. abyssinica on percent wound contraction in excision wound model.

Ointment	Day 4	Day 6	Day 8	Day 10	Day 12	Day 14	Day 16
SOB	7.60 ± 1.06	31.27 ± 1.06	48.27 ± 0.54	57.11 ± 0.98	70.1 ± 0.67	82.45 ± 0.62	90.63 ± 0.54
HCEO 5% w/w	16.12 ± 0.78a3	39.00 ± 1.22a3d1	55.56 ± 1.04a3c3d3	77.99 ± 0.92a3c3d3	90.58 ± 0.35a3c3d3	97.05 ± 0.20a3c2d2	99.55 ± 0.21a3
HCEO 10% w/w	17.69 ± 0.84a3	42.60 ± 0.45a3b3	64.81 ± 0.41a3b3	84.6 ± 0.25a3b3	94.18 ± 0.32a3b3	99.35 ± 0.22a3b2	100 ± 0.00a3
NO 0.2% w/v	17.46 ± 0.34a3	43.31 ± 0.79a3b3	63.7 ± 0.75a3b3	84.09 ± 0.53a3b3	93.73 ± 0.28a3b3	99.29 ± 0.26a3b2	100 ± 0.00a3

Data are expressed as mean ± SEM; n = 6; a, compared with simple ointment; b, compared with crude methanolic extract 5%(w/w); c, compared with crude methanolic extract 10% (w/w) ointment; d, compared with nitrofurazone 0.2%(w/v) ointment. 1, p < 0.05; 2, p < 0.01; 3, p < 0.001. SOB, simple ointment base; HCEO, hydromethanolic crude extract of B. abyssinica leaves; NO, nitrofurazone ointment.