Skip to main content
. 2021 Jul 1;95(8):2825–2838. doi: 10.1007/s00204-021-03102-3

Table 1.

List of compounds, CAS numbers, solvents, concentrations employed, and their respective RSG (%)

Compound CAS number Solvent* Concentrations** RSG
KBrO3 7758-01-2 H2O 0.313 mM 90
0.625 mM 85
1.25 mM 78
2.5 mM 40
MMS 66-27-3 DMSO 5 µM 98
10 µM 85
20 µM 80
40 µM 58
EMS 62-50-0 DMSO 0.5 µM 90
5 µM 84
50 µM 77
100 µM 40
BPDE 55097-80-8 DMSO 0.025 µM 93
0.05 µM 83
0.1 µM 70
0.2 µM 50
H2O2 7722-84-1 PBS 125 µM 92
250 µM 87
500 µM 79
CisPt 15663-27-1 H2O 0.83 µM 100
1.66 µM 100
3.33 µM 80
6.66 µM 39
13.33 µM 12
Mit. C 50-07-7 Medium 0.006 µM 98
0.03 µM 95
0.15 µM 82
0.3 µM 50
Triton X-100 9002-93-1 H2O 0.03 mM 60
0.1 mM 7
DMSO 67-68-5 Medium 1% 100
2% 95
4% 83
8% 80

*The final solvent concentration was 1% in all cases. **The three lowest concentrations of each compound were employed for the enzyme-modified comet assay. The same three concentrations and the highest one (the two highest in the case of CisPt) of each compound were used for the comet assay modified for ICL detection (except for H2O2 and Triton X-100)