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. 2021 Jun 21;9(8):e1077–e1087. doi: 10.1016/S2214-109X(21)00218-7

Table 4.

Estimates of global number of hPIV-attributable ALRI cases, hospital admissions, and deaths among children younger than 5 years in 2018 using attributable fraction of hPIV-associated ALRI

Attributable fraction (%)* Global hPIV–associated burden estimates (UR) Global hPIV–attributable burden estimates(UR)
ALRI cases (millions) 72% 26·1 (17·8–40·1) 18·8 (12·8–28·9)
ALRI hospital admissions (thousands) 72% 1007 (601–1750) 725 (433–1260)
ALRI deaths 65%§ 53 000 (25 300–113 500) 34 400 (16 400–73 800)

ALRI=acute lower respiratory infections. hPIV=human parainfluenza virus. UR=uncertainty range.

*

The fraction of ALRI cases and deaths with laboratory-confirmed hPIV that are attributable to hPIV.

Applying the corresponding attributable fraction to the estimates of hPIV–associated burden.

The attributable fraction for hPIV–associated ALRI cases was calculated using type-specific attributable fraction and prevalence. Details and the references are in the appendix (p 19).

§

The attributable fraction for hPIV-associated ALRI deaths was modelled using the attributable fraction for hPIV cases and the ratio of case-fatality between hPIV-attributable cases and hPIV-associated cases. Details are in the appendix (pp 20,21).